A key aspect of hair loss with age is the aging of the hair follicle.  Ordinarily, hair follicle renewal is maintained by the stem cells associated with each follicle. Aging of the hair follicle appears to be primed by a sustained cellular response to the DNA damage that accumulates in renewing stem cells during aging.  This damage response involves the proteolysis of type XVII collagen by neutrophil elastase in response to the DNA damage in the hair follicle stem cells. Proteolysis of collagen leads to elimination of the damaged cells and then to terminal hair follicle miniaturization.
Your skin tends to become thinner as you age. Therefore, it is important to take care of your skin in order to keep it supple and thickened. Thinning of the skin may occur when the level of collagen in the skin decreases and skin elasticity is lost. Collagen is a protein found in the skin which helps to nourish the skin and make it healthy. Thin skin may also be caused by the long-term use of steroid ointments that cause the skin to bruise easily and become fragile and transparent. Luckily, there are a number of things you can try to make your skin thicker, stronger and firmer.
I’ve also worked hard since I was twelve (now I’m 48) and my hands and arms have huge veins sticking up if I’m not off work for a day or two. BP is fine though since I went from 162 lbs to 113 lbs in 5 months. But, the parts I work with have sharp flash (plastics factory) and I’ll get those red slashes that make some people think it’s an Aids thing. NO, hubby and I have been faithful to each other for 20 years, this is just thin skin that has gotten thinner. And today I got the scrape over one of the veins and bled like crazy even though it was the most miniscule of nicks. Had blood dripping and curling around my wrist, for heaven’s sake.